Oct 24, 2016 · Houston’s relationship with “lean,” or codeine-promethazine, goes back to at least the 1960s, when blues musicians would mix Robitussin with alcohol. These musicians lived in the same ... Promethazine with codeine syrup is indicated for the temporary relief of coughs and upper respiratory tract symptoms related to allergies or the common cold. What is promethazine used for? Promethazine is an antihistamine, similar to products available over-the-counter like Benadryl, Claritin, Zyrtec, and Allegra. Antihistamines are typically ...Generic name: promethazine hydrochloride and codeine phosphate Dosage form: oral solution Drug class: Upper respiratory combinations Medically reviewed by Drugs.com. Last updated on Jan 1, 2022. On This Page Indications and Usage Dosage and Administration Dosage Forms and Strengths Contraindications Warnings and PrecautionsCodeine Dosage and Administration General Managing Opiate Therapy for Acute Pain. Optimize concomitant use of other appropriate therapies. When opiate analgesia required, use conventional (immediate-release) opiates in smallest effective dosage and for shortest possible duration, since long-term opiate use often begins with treatment of acute pain.Cough and Cold Medicines • May 2014 • Page 2 ! Drinking!promethazine(codeinecough syrup!mixed!with!soda!(a!combination! calledsyrup,sizzurp,purpledrank,barre, Jan 27, 2023 · Promethazine VC with Codeine Oral Solution is a combination of codeine, an opioid agonist; promethazine, a phenothiazine; and phenylephrine, an alpha-1 adrenergic receptor agonist, indicated for the temporary relief of cough and upper respiratory symptoms, including nasal congestion, associated with allergy or the common cold in patients 18 years of age and older. Jul 20, 2021 · Codeine is a drug in some prescription pain medicines. It is in the class of drugs known as opioids, which refers to any synthetic, semisynthetic, or natural drug that has morphine-like properties. Codeine overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose. This ... Avoid sunlamps and tanning beds. This medicine may cause dryness of the mouth. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist.Aug 4, 2023 · What is Codeine Phosphate-Promethazine HCl? Codeine Phosphate-Promethazine HCl is a combination medicine used to treat cold or allergy symptoms such as runny nose, sneezing, and cough. Codeine Phosphate-Promethazine HCl contains an opioid (narcotic) cough medicine, and may be habit-forming. Codeine Phosphate-Promethazine HCl may also be used ... Promethazine and codeine combination is used to relieve cough, runny or stuffy nose, sneezing, or other symptoms caused by allergies or the common cold. Promethazine is an antihistamine. It works by preventing the effects of a substance called histamine, which is produced by the body.Promethazine Hydrochloride and Codeine Phosphate Syrup is a prescription medicine used to temporarily treat cough and upper respiratory symptoms that you can have with allergies or a common cold. Promethazine Hydrochloride and Codeine Phosphate Syrup contains 2 medicines, promethazine and codeine. Promethazine is an antihistamine.Aug 4, 2023 · Promethazine 6.25 mg/ Codeine 10 mg per 5 mL: Average effective dose: 5 mL orally every 4 to 6 hours as needed. Maximum dose: 30 mL (promethazine 37.5 mg; codeine: 60 mg) in 24 hours. Comments: Liquid preparations should be measured with an accurate milliliter measuring device. Uses: Temporary relief of coughs and upper respiratory symptoms ... Initial dose: 15 to 60 mg orally up to every 4 hours as needed. Maximum dose: 360 mg in 24 hours. Comments: Initial doses should be individualized taking into account severity of pain, response, prior analgesic treatment experience, and risk factors for addiction, abuse, and misuse. Doses higher than 60 mg have not been shown to improve pain ...Codeine is used to relieve mild to moderately severe pain, and it belongs to the drug class of opioid analgesics. Codeine has also been prescribed to prevent coughing, though the antitussive administration is most often in liquid formulations and in conjunction with other medications. ( 1, 2) The hepatic CYP2D6 enzyme metabolizes a quarter of ...Find patient medical information for promethazine oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. ... (such as codeine, hydrocodone), ...Jul 20, 2021 · Codeine is a drug in some prescription pain medicines. It is in the class of drugs known as opioids, which refers to any synthetic, semisynthetic, or natural drug that has morphine-like properties. Codeine overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose. This ... See full list on drugs.com Houston’s relationship with “lean,” or codeine-promethazine, goes back to at least the 1960s, when blues musicians would mix Robitussin with alcohol. These musicians lived in the same ...Codeine Information. Codeine is an opioid pain reliever used to treat mild to moderately severe pain. It is also used, usually in combination with other medications, to reduce coughing. Codeine is ...Oct 10, 2022 · Initial dose: 15 to 60 mg orally up to every 4 hours as needed. Maximum dose: 360 mg in 24 hours. Comments: Initial doses should be individualized taking into account severity of pain, response, prior analgesic treatment experience, and risk factors for addiction, abuse, and misuse. Doses higher than 60 mg have not been shown to improve pain ... NHS medicines information on codeine – what it's used for, side effects, dosage and who can take it.What is codeine and promethazine? Codeine and promethazine is a combination medicine used to treat cold or allergy symptoms such as runny nose, sneezing, and cough. Codeine and promethazine contains an opioid (narcotic) cough medicine, and may be habit-forming. Codeine and promethazine may also be used for purposes not listed in this medication ...Generic name: codeine / promethazine systemic Drug class: upper respiratory combinations. For consumers: dosage, interactions, side effects. For professionals: Prescribing Information. Expand current row for information about Hycodan Hycodan: 8.5 Codeine is also used to treat diarrhoea. It works in the central nervous system and the brain to block pain signals to the rest of the body. It also reduces the anxiety and stress caused by pain. Codeine is available on prescription and comes as tablets, a liquid you swallow and as an injection. Codeine injections are usually only given in ...Promethazine is an antihistamine that relieves watery eyes, itchy eyes /nose/throat, runny nose, and sneezing. Codeine is an opioid cough suppressant ( antitussive) that affects a certain part...Promethazine HCl and Codeine Phosphate Oral Solution in adolescents 12 to 18 years of age who have other risk factors that may increase their sensitivity to the respiratory depressant effects of codeine. Promethazine and Respiratory Depression in Children Postmarketing cases of respiratory depression, including fatalities have been reported with Anecdotal promethazine misuse/abuse reports have been confirmed by European Monitoring Agency data. Promethazine misuse/abuse appears to be an alarming issue, being associated with drug-related fatalities. Thus, healthcare professionals should be warned about a possible misuse of promethazine and be …Codeine is a drug in some prescription pain medicines. It is in the class of drugs known as opioids, which refers to any synthetic, semisynthetic, or natural drug that has morphine-like properties. Codeine overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose. Promethazine is a phenothiazine medication that blocks the signals in your brain and body causing you to experience cold and allergy symptoms like a runny nose and sneezing. Codeine is an opioid medication that works in your brain to lessen your urge to cough. What is Promethazine / codeine used for?Codeine is a drug in some prescription pain medicines. It is in the class of drugs known as opioids, which refers to any synthetic, semisynthetic, or natural drug that has morphine-like properties. Codeine overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose. In the early 1990s, several studies reported the misuse of codeine and promethazine hydrochloride cough syrup. Since then, the combination of this pharmaceutical, together with sprite or alcohol, known on the streets as "purple drank" or "lean", has become a popular drug among rap singers who promot …Codeine Information. Codeine is an opioid pain reliever used to treat mild to moderately severe pain. It is also used, usually in combination with other medications, to reduce coughing. Codeine is ...codeine. Used for Pain. Codeine is an opioid pain medication that's taken by mouth and used to treat mild-to-moderate pain. Common side effects of codeine include constipation, itching, sleepiness, and dizziness. It's typically not a first-choice pain medication because it can lead to more serious harm, such as slowed breathing and addiction.Codeine and promethazine es una medicina combinada se usa para el tratamiento de los síntomas del resfrío o alergias como nariz mocosa, estornudos, y tos. Codeine and promethazine contiene una medicina opioide (narcótico) para la tos, y puede crear hábito. . Codeine and promethazine puede también usarse para fines no... ozanimod. ozanimod and codeine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Avoid or Use Alternate Drug. Because the active metabolite of ozanimod inhibits MAO-B in vitro, there is a potential for serious adverse reactions, including hypertensive crisis. Promethazine Prescription only Codeine is an effective pain reliever; however, it is addictive, may cause constipation, and its pain-relieving effects vary markedly between individuals. Codeine should only be used for pain relief... more Prescription only Promethazine may be used to relieve allergy symptoms and nausea.Codeine (3-methylmorphine) is an alkaloid prepared from the methylation of morphine derived from poppy seeds ( Papaver somniferum) [ 1 ]. It is used to manage mild to moderate pain, including chronic cancer pain, and has antitussive, antistress, and antidiarrheal properties [ 2, 3, 4 ]. In the body, a small amount of codeine is metabolized to ...Each 5 mL (one teaspoonful), for oral administration contains: Promethazine hydrochloride 6.25 mg; codeine phosphate 10 mg. Alcohol 7%. Inactive Ingredients: Ascorbic acid, citric acid, FD&C ... Codeine: Narcotic analgesics, including codeine, exert their primary effects on the central nervous system and gastrointestinal tract. The analgesic ...Descriptions. Acetaminophen and codeine combination is used to relieve mild to moderate pain. Acetaminophen is used to relieve pain and reduce fever in patients. It does not become habit-forming when taken for a long time. But acetaminophen may cause other unwanted effects when taken in large doses, including serious liver damage.Adults and children 12 years of age and older—5 milliliters (mL) (1 teaspoonful) every 4 to 6 hours. Do not take more than 30 mL in 24 hours. Children 6 to 11 years of age—2.5 to 5 mL (0.5 to 1 teaspoonful) every 4 to 6 hours. Do not take more than 30 mL in 24 hours. Children younger than 6 years of age—Use is not recommended. Missed DoseSep 14, 2022 · Promethazine Dosage and Administration Administration. Administer orally, rectally, or by deep IM injection. Also administered by IV injection. However, FDA states that deep IM injection is the preferred method for administration of promethazine hydrochloride injection because of risks associated with IV administration (see Warnings Regarding Parenteral Administration under Boxed Warning). Generic Name (S): codeine-guaifenesin. Warnings: This medication has a risk for abuse and addiction, which can lead to overdose and death. This medication may also cause severe, possibly fatal ...Generic Name (S): codeine-guaifenesin. Warnings: This medication has a risk for abuse and addiction, which can lead to overdose and death. This medication may also cause severe, possibly fatal ...Aug 6, 2023 · Hycofenix, Rezira (hydrocodone, pseudoephedrine, guaifenesin) Tussionex, Pennkinetic, Vituz (hydrocodone, chlorpheniramine, pseudoephedrine) Generic combinations of hydrocodone and homatropine. Giving prescription cough medicines to kids or teens is dangerous. They can slow their breathing to dangerous levels and can even be fatal. Aug 4, 2023 · What is Codeine Phosphate-Promethazine HCl? Codeine Phosphate-Promethazine HCl is a combination medicine used to treat cold or allergy symptoms such as runny nose, sneezing, and cough. Codeine Phosphate-Promethazine HCl contains an opioid (narcotic) cough medicine, and may be habit-forming. Codeine Phosphate-Promethazine HCl may also be used ... after a dosage increase. if you are older. if you have an existing lung problem. The side effects of codeine are similar to those of other opioids, and include: constipation. headache or dizziness. fatigue or drowsiness (especially soon after a dose) loss of appetite, nausea and vomiting. Always take medicines exactly as prescribed your doctor. Tramadol and codeine are both opioids or opiates used to control pain. Codeine is also used as a cough medication. Both codeine and tramadol are habit forming. The most frequent side effects of codeine and tramadol include lightheadedness, dizziness, nausea, vomiting, shortness of breath, sedation, allergic reactions, constipation, abdominal pain, rash, itching, and addiction.-Codeine (an opiate that treats pain and coughs) -Hydrocodone (an opiate used to treat moderate to severe pain) -Phenacetin (an analgesic that's not used much anymore)of codeine due to a CYP2D6 polymorphism. Promethazine HCl and Codeine Phosphate Oral Solution is contraindicated in children younger than 12 years of age and in children younger than 18 years of age following tonsillectomy and/or adenoidectomy (see CONTRAINDICATIONS). Avoid the use of Promethazine HCl and Codeine PhosphateJan 20, 2021 · Typical dosing for Robitussin AC (guaifenesin / codeine) Adults and children over 12 years old: The typical dose is 2 teaspoonfuls (10 mL) by mouth every 4 hours as needed. Children between 6 and 12 years old: The typical dose is 1 teaspoonful (5 mL) by mouth every 4 hours as needed. Children under 6 years old: Speak with your child's provider. Codeine is used to relieve mild to moderate pain. It belongs to the group of medicines called narcotic analgesics (pain medicines). This medicine acts on the central nervous system (CNS) to relieve pain. When codeine is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing ...Promethazine HCl and Codeine Phosphate Oral Solution exposes patients and other users to the risks of opioid addiction, abuse, and misuse, which can lead to overdose and death. Reserve Promethazine HCl and Codeine Phosphate Oral Solution for use in adult patients for whom thecodeine/promethazine systemic. Drug class: upper respiratory combinations. Codeine/promethazine systemic is used in the treatment of: Cough; codeine/pseudoephedrine systemic. Brand names: Cycofed, Nucodine, Codar D, Nucofed, EndaCof-DC Drug class: upper respiratory combinations. Codeine/pseudoephedrine systemic is used in the treatment of: A total of 486 drugs are known to interact with codeine / guaifenesin : 122 major drug interactions (477 brand and generic names) 361 moderate drug interactions (1496 brand and generic names) 3 minor drug interactions (7 brand and generic names) A total of 748 drugs are known to interact with codeine / promethazine : 181 major drug interactions ...May 5, 2020 · Promethazine with Codeine Oral Solution is a combination of codeine, an opioid agonist; and promethazine, a phenothiazine, indicated for the temporary relief of cough and upper respiratory symptoms associated with allergy or the common cold in patients 18 years of age and older. NHS medicines information on codeine – what it's used for, side effects, dosage and who can take it.Codeine and promethazine es una medicina combinada se usa para el tratamiento de los síntomas del resfrío o alergias como nariz mocosa, estornudos, y tos. Codeine and promethazine contiene una medicina opioide (narcótico) para la tos, y puede crear hábito. . Codeine and promethazine puede también usarse para fines no... Typical dosing for Robitussin AC (guaifenesin / codeine) Adults and children over 12 years old: The typical dose is 2 teaspoonfuls (10 mL) by mouth every 4 hours as needed. Children between 6 and 12 years old: The typical dose is 1 teaspoonful (5 mL) by mouth every 4 hours as needed. Children under 6 years old: Speak with your child's provider.Promethazine Dosage and Administration Administration. Administer orally, rectally, or by deep IM injection. Also administered by IV injection. However, FDA states that deep IM injection is the preferred method for administration of promethazine hydrochloride injection because of risks associated with IV administration (see Warnings Regarding Parenteral Administration under Boxed Warning).Hycofenix, Rezira (hydrocodone, pseudoephedrine, guaifenesin) Tussionex, Pennkinetic, Vituz (hydrocodone, chlorpheniramine, pseudoephedrine) Generic combinations of hydrocodone and homatropine. Giving prescription cough medicines to kids or teens is dangerous. They can slow their breathing to dangerous levels and can even be fatal.Jul 20, 2021 · Codeine is a drug in some prescription pain medicines. It is in the class of drugs known as opioids, which refers to any synthetic, semisynthetic, or natural drug that has morphine-like properties. Codeine overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose. This ... Phenergan is also found in combination with other medications such as phenylephrine (Prometh Hydrochloride), codeine (Prometh VC), or dextromethorphan (Promethazine DM) What is Phenergan? Phenergan belongs to a group of drugs called phenothiazines. It works by changing the actions of chemicals in your brain. Promethazine also acts as an ...Jan 10, 2021 · Promethazine is a phenothiazine medication that blocks the signals in your brain and body causing you to experience cold and allergy symptoms like a runny nose and sneezing. Codeine is an opioid medication that works in your brain to lessen your urge to cough. Schedule 5 (V) Drugs. The drug has a low potential for abuse relative to the drugs in schedule 4. The drug has a currently accepted medical use in treatment in the United States. Lean is a very sweet drink that blends soda with cough syrup containing codeine. Some formulas also add candy or sweetening syrup. Users may also mix in promethazine, which is an antihistamine ...Promethazine 6.25 mg/ Codeine 10 mg per 5 mL: Average effective dose: 5 mL orally every 4 to 6 hours as needed. Maximum dose: 30 mL (promethazine 37.5 mg; codeine: 60 mg) in 24 hours. Comments: Liquid preparations should be measured with an accurate milliliter measuring device. Uses: Temporary relief of coughs and upper respiratory symptoms ...Aug 4, 2023 · Promethazine 6.25 mg/ Codeine 10 mg per 5 mL: Average effective dose: 5 mL orally every 4 to 6 hours as needed. Maximum dose: 30 mL (promethazine 37.5 mg; codeine: 60 mg) in 24 hours. Comments: Liquid preparations should be measured with an accurate milliliter measuring device. Uses: Temporary relief of coughs and upper respiratory symptoms ... Tussionex doesn’t belong in the “colored” syrups conversation. Codeine and euphoria don’t belong in the same sentence. It’s the promethazine and codeine combo that gets you “high”. Hydrocodone (especially in the tussionex time release form) isn’t even in the same class as codeine. Tuss is by far the best cough syrup ever madeAug 1, 2023 · Adults and children 12 years of age and older—5 milliliters (mL) (1 teaspoonful) every 4 to 6 hours. Do not take more than 30 mL in 24 hours. Children 6 to 11 years of age—2.5 to 5 mL (0.5 to 1 teaspoonful) every 4 to 6 hours. Do not take more than 30 mL in 24 hours. Children younger than 6 years of age—Use is not recommended. Missed Dose Lean, also known as purple drank, purp, sizzurp, syrup, wock or oil, and several other names, is a recreational drug beverage, prepared by mixing prescription strength cough or cold syrup containing codeine and promethazine with a soft drink. The beverage originated in Houston and is popular in hip hop culture, especially within the Southern ... Sep 14, 2018 · Codeine is a prescription opioid, which is used as a pain reliever, and promethazine is an antihistamine. Both drugs have sedative effects and can produce feelings of drowsiness, mild euphoria and ... Jul 20, 2021 · Codeine is a drug in some prescription pain medicines. It is in the class of drugs known as opioids, which refers to any synthetic, semisynthetic, or natural drug that has morphine-like properties. Codeine overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose. This ... Promethazine is an antihistamine. It works by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes. It can sometimes close up the bronchial tubes (air passages of the lungs) and make breathing difficult. Codeine belongs to the group of medicine ...of codeine due to a CYP2D6 polymorphism. Promethazine HCl and Codeine Phosphate Oral Solution is contraindicated in children younger than 12 years of age and in children younger than 18 years of age following tonsillectomy and/or adenoidectomy (see CONTRAINDICATIONS). Avoid the use of Promethazine HCl and Codeine Phosphate Oct 10, 2022 · Initial dose: 15 to 60 mg orally up to every 4 hours as needed. Maximum dose: 360 mg in 24 hours. Comments: Initial doses should be individualized taking into account severity of pain, response, prior analgesic treatment experience, and risk factors for addiction, abuse, and misuse. Doses higher than 60 mg have not been shown to improve pain ... Avoid sunlamps and tanning beds. This medicine may cause dryness of the mouth. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist.Codeine cough suppressants like promethazine/codeine should only be an option for short-term use — and only in adults. This type of cough syrup is available by prescription. However, it is a controlled substance and habit-forming. Best cough medicine for kidsJan 10, 2021 · Pharmacological properties of promethazine. Promethazine is a phenothiazine derivative and a histamine (H1) receptor antagonist that is commonly used for symptomatic relief of nausea and vomiting, for allergic conditions, motion sickness and common cold, and for short-term use treatment of insomnia in adults or as a paediatric sedative (). Uses for Phenergan w/Codeine. Promethazine and codeine combination is used to relieve cough, runny or stuffy nose, sneezing, or other symptoms caused by allergies or the common cold. Promethazine is an antihistamine. It works by preventing the effects of a substance called histamine, which is produced by the body.Aug 4, 2023 · Promethazine 6.25 mg/ Codeine 10 mg per 5 mL: Average effective dose: 5 mL orally every 4 to 6 hours as needed. Maximum dose: 30 mL (promethazine 37.5 mg; codeine: 60 mg) in 24 hours. Comments: Liquid preparations should be measured with an accurate milliliter measuring device. Uses: Temporary relief of coughs and upper respiratory symptoms ... Each 5 mL (one teaspoonful), for oral administration contains: Promethazine hydrochloride 6.25 mg; codeine phosphate 10 mg. Alcohol 7%. Inactive Ingredients: Ascorbic acid, citric acid, FD&C ... Codeine: Narcotic analgesics, including codeine, exert their primary effects on the central nervous system and gastrointestinal tract. The analgesic ...
Jan 29, 2020 · Lean is a very sweet drink that blends soda with cough syrup containing codeine. Some formulas also add candy or sweetening syrup. Users may also mix in promethazine, which is an antihistamine ... . Dollar500 down cars austin tx
Generic name: codeine / promethazine systemic Drug class: upper respiratory combinations. For consumers: dosage, interactions, side effects. For professionals: Prescribing Information. Expand current row for information about Hycodan Hycodan: 8.5 The most frequently reported codeine-containing medicines in the cases were acetaminophen with codeine used for pain, and promethazine with codeine (with or without phenylephrine) used for cough ... Codeine Information. Codeine is an opioid pain reliever used to treat mild to moderately severe pain. It is also used, usually in combination with other medications, to reduce coughing. Codeine is ...Aug 4, 2023 · What is codeine and promethazine? Codeine and promethazine is a combination medicine used to treat cold or allergy symptoms such as runny nose, sneezing, and cough. Codeine and promethazine contains an opioid (narcotic) cough medicine, and may be habit-forming. Codeine and promethazine may also be used for purposes not listed in this medication ... Dec 13, 2022 · severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out. Side effects such as confusion and severe drowsiness may be more likely in older adults. Common promethazine side effects may include: drowsiness, dizziness; ringing in your ears; codeine/promethazine systemic. Drug class: upper respiratory combinations. Codeine/promethazine systemic is used in the treatment of: Cough; codeine/pseudoephedrine systemic. Brand names: Cycofed, Nucodine, Codar D, Nucofed, EndaCof-DC Drug class: upper respiratory combinations. Codeine/pseudoephedrine systemic is used in the treatment of:codeine/promethazine systemic. Drug class: upper respiratory combinations. Codeine/promethazine systemic is used in the treatment of: Cough; codeine/pseudoephedrine systemic. Brand names: Cycofed, Nucodine, Codar D, Nucofed, EndaCof-DC Drug class: upper respiratory combinations. Codeine/pseudoephedrine systemic is used in the treatment of: Generic Name (S): codeine-guaifenesin. Warnings: This medication has a risk for abuse and addiction, which can lead to overdose and death. This medication may also cause severe, possibly fatal ...Descriptions. Acetaminophen and codeine combination is used to relieve mild to moderate pain. Acetaminophen is used to relieve pain and reduce fever in patients. It does not become habit-forming when taken for a long time. But acetaminophen may cause other unwanted effects when taken in large doses, including serious liver damage.Aug 4, 2023 · What is Codeine Phosphate-Promethazine HCl? Codeine Phosphate-Promethazine HCl is a combination medicine used to treat cold or allergy symptoms such as runny nose, sneezing, and cough. Codeine Phosphate-Promethazine HCl contains an opioid (narcotic) cough medicine, and may be habit-forming. Codeine Phosphate-Promethazine HCl may also be used ... Sep 20, 2012 · Codeine is used to relieve mild to moderately severe pain, and it belongs to the drug class of opioid analgesics. Codeine has also been prescribed to prevent coughing, though the antitussive administration is most often in liquid formulations and in conjunction with other medications. ( 1, 2) The hepatic CYP2D6 enzyme metabolizes a quarter of ... Jul 14, 2021 · Like other opioids, codeine can be toxic in large amounts. Symptoms of an opioid overdose include: bluish fingernails and lips. confusion. breathing problems, such as slow and labored breathing ... Oct 10, 2022 · Initial dose: 15 to 60 mg orally up to every 4 hours as needed. Maximum dose: 360 mg in 24 hours. Comments: Initial doses should be individualized taking into account severity of pain, response, prior analgesic treatment experience, and risk factors for addiction, abuse, and misuse. Doses higher than 60 mg have not been shown to improve pain ... Promethazine Dosage and Administration Administration. Administer orally, rectally, or by deep IM injection. Also administered by IV injection. However, FDA states that deep IM injection is the preferred method for administration of promethazine hydrochloride injection because of risks associated with IV administration (see Warnings Regarding Parenteral Administration under Boxed Warning).Adults and children 12 years of age and older—5 milliliters (mL) (1 teaspoonful) every 4 to 6 hours. Do not take more than 30 mL in 24 hours. Children 6 to 11 years of age—2.5 to 5 mL (0.5 to 1 teaspoonful) every 4 to 6 hours. Do not take more than 30 mL in 24 hours. Children younger than 6 years of age—Use is not recommended. Missed DosePromethazine HCl and Codeine Phosphate Oral Solution exposes patients and other users to the risks of opioid addiction, abuse, and misuse, which can lead to overdose and death. Reserve Promethazine HCl and Codeine Phosphate Oral Solution for use in adult patients for whom thePromethazine is an antihistamine that relieves watery eyes, itchy eyes /nose/throat, runny nose, and sneezing. Codeine is an opioid cough suppressant ( antitussive) that affects a certain part...May 2, 2014 · Promethazine with codeine syrup is indicated for the temporary relief of coughs and upper respiratory tract symptoms related to allergies or the common cold. What is promethazine used for? Promethazine is an antihistamine, similar to products available over-the-counter like Benadryl, Claritin, Zyrtec, and Allegra. Antihistamines are typically ... Aug 27, 2009 · Each 5 mL (one teaspoonful), for oral administration contains: Promethazine hydrochloride 6.25 mg; codeine phosphate 10 mg. Alcohol 7%. Inactive Ingredients: Ascorbic acid, citric acid, FD&C ... Codeine: Narcotic analgesics, including codeine, exert their primary effects on the central nervous system and gastrointestinal tract. The analgesic ... 5.1 Addiction, Abuse, and Misuse. Promethazine with Codeine Oral Solution contains codeine, a Schedule V controlled substance. As an opioid, Promethazine with Codeine Oral Solution exposes users to the risks of addiction, abuse, and misuse [see DRUG ABUSE AND DEPENDENCE (9)], which can lead to overdose and death [seeOVERDOSAGE (10)].Lean, also known as purple drank, purp, sizzurp, syrup, wock or oil, and several other names, is a recreational drug beverage, prepared by mixing prescription strength cough or cold syrup containing codeine and promethazine with a soft drink. The beverage originated in Houston and is popular in hip hop culture, especially within the Southern ....